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In parallel to albuminuria in 1936, discussion on renal lesions observed in patients with diabetes led to the description, by Kimmelstiel and Wilson, of the characteristic nodular fibrotic observed in the diabetic glomeruli (Kimmelstiel and Wilson, 1936b). Kimmelstiel and Wilson introduced the term diabetic nephropathy (DN) to define a clinical ...
Diabetic nephropathy is the most common cause of end-stage renal disease and is a serious complication that affects approximately one quarter of adults with diabetes in the United States. [ 13 ] [ 14 ] Affected individuals with end-stage kidney disease often require hemodialysis and eventually kidney transplantation to replace the failed kidney ...
Osteoarthritis of the hand causes stiffness of the base of the thumb, alongside enlargement of DIP and PIP joints, leading to the formation of Heberden's nodes and Bouchard's nodes respectively. [6] Such firm and bony swellings at the finger joints are caused by the growth of osteophytes .
Wartenberg's sign is a neurological sign consisting of involuntary abduction of the fifth (little) finger, caused by unopposed action of the extensor digiti minimi. [ 1 ] [ 2 ] This commonly results from weakness of some of the ulnar nerve innervated intrinsic hand muscles -in particular the palmar interosseous muscle to the little finger ...
A hand imitating an ulnar claw. The metacarpophalangeal joints of the 4th and 5th fingers are extended and the Interphalangeal joints of the same fingers are flexed.. An ulnar claw, also known as claw hand or Spinster’s Claw, is a deformity or an abnormal attitude of the hand that develops due to ulnar nerve damage causing paralysis of the lumbricals.
Diabetic cheiroarthropathy, also known as diabetic stiff hand syndrome or limited joint mobility syndrome, is a cutaneous condition characterized by waxy, thickened skin and limited joint mobility of the hands and fingers, leading to flexion contractures, a condition associated with diabetes mellitus [1]: 681 and it is observed in roughly 30% of diabetic patients with longstanding disease.
From shaking hands to sharing towels at the pool, hand warts are easily spread. What causes warts on hands? Here's what types of HPV can trigger this contagious skin condition.
Different forms of micrographia. Micrographia is an acquired disorder characterized by abnormally small, cramped handwriting. [1] It is commonly associated with neurodegenerative disorders of the basal ganglia, such as in Parkinson's disease, but it has also been ascribed to subcortical focal lesions. [2]