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Hamman's syndrome, also known as Macklin's syndrome, is a syndrome of spontaneous subcutaneous emphysema [1] (air in the subcutaneous tissues of the skin) and pneumomediastinum (air in the mediastinum, the center of the chest cavity), sometimes associated with pain and, less commonly, dyspnea (difficulty breathing), dysphonia, and a low-grade fever.
Pneumomediastinum can also be characterized by the shortness of breath that is typical of a respiratory system problem. It is often recognized on auscultation by a "crunching" sound timed with the cardiac cycle (Hamman's crunch). Pneumomediastinum may also present with symptoms mimicking cardiac tamponade as a result of the increased ...
Hamman's sign (rarely, Hammond's sign [1] or Hammond's crunch [2]) is a medical sign consisting of a crunching, rasping sound, synchronous with the heartbeat, [3] heard over the precordium in spontaneous mediastinal emphysema. It is thought to result from the heart beating against air-filled tissues.
On a chest X-ray, the sail sign is a radiologic sign that suggests left lower lobe collapse. [1] In children, however, a sail sign could be normal, reflecting the shadow of the thymus. [2] The thymic sail sign or spinnaker-sail sign is due to elevation of the thymic lobes in the setting of pneumomediastinum. [3]
[1] Pneumomediastinum can result from a number of events. For example, foreign body aspiration, in which someone inhales an object, can cause pneumomediastinum (and lead to subcutaneous emphysema) by puncturing the airways or by increasing the pressure in the affected lung(s) enough to cause them to burst. [17]
Pulmonary interstitial emphysema (PIE) is a collection of air outside of the normal air space of the pulmonary alveoli, found instead inside the connective tissue of the peribronchovascular sheaths, interlobular septa, and visceral pleura.
Package inserts for prescription drugs often include a separate document called a "patient package insert" with information written in plain language intended for the end-user—the person who will take the drug or give the drug to another person, such as a minor. Inserts for over-the-counter medications are also written plainly. [1] [2]
Pneumoperitoneum is pneumatosis (abnormal presence of air or other gas) in the peritoneal cavity, a potential space within the abdominal cavity.The most common cause is a perforated abdominal organ, generally from a perforated peptic ulcer, although any part of the bowel may perforate from a benign ulcer, tumor or abdominal trauma.