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Neonatal diabetes is a genetic disease, caused by genetic variations that were either spontaneously acquired or inherited from one's parents. At least 30 distinct genetic variants can result in neonatal diabetes. [8] The development and treatment of neonatal diabetes will vary based on the particular genetic cause.
Permanent neonatal diabetes mellitus (PNDM) is a newly identified and potentially treatable form of monogenic diabetes. This type of neonatal diabetes is caused by activating mutations of the KCNJ11 gene, which codes for the Kir6.2 subunit of the beta cell K ATP channel. [1] [2] This disease is considered to be a type of maturity onset diabetes ...
Transient neonatal diabetes mellitus (TNDM) is a form of neonatal diabetes presenting at birth that is not permanent.
July 1, 1982 January 7, 1985 Duane Alexander: February 5, 1986 September 30, 2009 Susan Shurin (acting) October 1, 2009 November 30, 2009 Alan Edward Guttmacher (acting) December 1, 2009 July 21, 2010 Alan Edward Guttmacher: July 22, 2010 September 30, 2015 Catherine Y. Spong (acting) October 1, 2015 October 31, 2016 Diana W. Bianchi: November ...
The National Association of Neonatal Nurses (NANN) is a professional organization for neonatal nurses in the United States. NANN was founded in 1984 by five neonatal nurses: Patricia Johnson, Linda Bellig, Tracy Karp, Charles Rait and Donna Lee Loper. Within one year, the association boasted a membership of 3,790. [1]
National Diabetes Education Program (NDEP) was started by the NIH and CDC in 1997 to educate the public about the risks of diabetes. [1] NDEP's goal was to reduce the illness and death caused by diabetes and its complications. To help meet this goal, NDEP provided free diabetes education information to the public. NDEP ended in 2019. [2]
Pre-gestational diabetes can be classified as Type 1 or Type 2 depending on the physiological mechanism. Type 1 diabetes mellitus is an autoimmune disorder leading to destruction of insulin-producing cell in the pancreas; type 2 diabetes mellitus is associated with obesity and results from a combination of insulin resistance and insufficient insulin production.
Maturity-onset diabetes of the young (MODY) refers to any of several hereditary forms of diabetes mellitus caused by mutations in an autosomal dominant gene disrupting insulin production. [1] Along with neonatal diabetes , MODY is a form of the conditions known as monogenic diabetes.