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Propranolol may cause harmful effects for the baby if taken during pregnancy; [7] however, its use during breastfeeding is generally considered to be safe. [8] It is a non-selective beta blocker which works by blocking β-adrenergic receptors. [2] Propranolol was patented in 1962 and approved for medical use in 1964. [9]
Pink noise may be a helpful intervention for improving sleep outcomes, per a 2022 review in the Journal of Clinical Sleep Medicine. However, Dr. Dasgupta points out that more research is needed to ...
The first beta blocker, propranolol, was introduced in the early 1960s by the winner of The Nobel Prize in Physiology or Medicine 1988- Sir James W. Black. [23] The drug was originally developed in order to induce a calm effect on the heart by blocking the beta receptor for adrenaline, treating a range of cardiovascular disorders. [23]
Primidone is not indicated for essential tremor but is often used as a first-line therapy for essential tremor, as is propranolol. In tremor amplitude reduction, it is just as effective as propranolol, reducing it by 50%. Both drugs are well studied for this condition, unlike other therapies, and are recommended for initial treatment.
Older adults with calcium and magnesium deficiencies also had poorer cognitive performance compared to peers with adequate micronutrient levels, a recent study has found.
The review found no suitable evidence to support the current guidelines recommending its use. [32] A 2017 Cochrane review on the use of beta blockers to prevent aortic dissections in people with Marfan syndrome was unable to draw definitive conclusions due to lack of evidence. [33] Adrenergic antagonists are mostly used for cardiovascular disease.
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