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Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1 -antihistamine and it works by blocking certain effects of histamine , which produces its antihistamine and sedative effects.
On December 2, 1975, the FDA ordered Sominex 2, which included diphenhydramine, to be removed from the market because the packaging was not child-resistant and the label did not include necessary warnings. [22] They also stated that the use of diphenhydramine in an OTC drug was illegal. [37]
Benadryl Allergy is widely used as a sleep aid among adults. While it is not marketed as an over-the-counter (OTC) sleeping aid, most versions of Benadryl contain diphenhydramine, a drug with sedative properties. [6] Diphenhydramine (Benadryl) has also been used by parents to help improve their infant's sleep habits.
Doses and Warnings Sedation and Motion Sickness Before a Car Ride The standard dose is about the same, 1–2 mg per pound of body weight, but a slightly higher dose of 3 mg per pound may be ...
Multiple teens have been hospitalized after ingesting up to 14 Benadryl doses at once, inspired by a TikTok challenge aimed at hallucinating. Experts say the activity could be deadly.
The first-generation sedating antihistamines diphenhydramine, doxepin, doxylamine, and pyrilamine are the most widely used medications in the world for preventing and treating insomnia. [6] As of 2004, doxylamine and diphenhydramine, which are both over-the-counter medications, were the agents most commonly used to treat short-term insomnia. [11]
The Summary. Flooding in North Carolina following Hurricane Helene has led to swarms of yellow jackets. Heavy rain and standing water likely destroyed the insects' nests underground and in trees.
In 2020, purposeful overmedication with Benadryl (diphenhydramine) was a concern due to use of social media by teenagers in the United States, with the FDA issuing a public warning about the possibility of seizures, hallucinations, breathing difficulty or loss of consciousness. [8]