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In mammalian brain anatomy, the prefrontal cortex (PFC) covers the front part of the frontal lobe of the cerebral cortex. It is the association cortex in the frontal lobe. [ 2 ] The PFC contains the Brodmann areas BA8 , BA9 , BA10 , BA11 , BA12 , BA13 , BA14 , BA24 , BA25 , BA32 , BA44 , BA45 , BA46 , and BA47 .
The association cortex is a part of the cerebral cortex that performs complex cognitive functions. [ 1 ] [ 2 ] Unlike primary sensory or motor areas , which process specific sensory inputs or motor outputs, the association cortex integrates information from various sources to support higher-order cognitive processes.
The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes of the brain which is involved in the cognitive process of decision-making.In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47.
The DLPFC has connections with the orbitofrontal cortex, as well as the thalamus, parts of the basal ganglia (specifically, the dorsal caudate nucleus), the hippocampus, and primary and secondary association areas of neocortex (including posterior temporal, parietal, and occipital areas).
The cerebral cortex, also known as the cerebral mantle, [1] is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals.It is the largest site of neural integration in the central nervous system, [2] and plays a key role in attention, perception, awareness, thought, memory, language, and consciousness.
The association areas of the human brain are highly developed, and are thought to play an integral role in complex functions. [3] The association areas can be divided into 3 categories: the parasensory association cortex, the frontal association cortex, and the paralimbic association cortex. [3]
In neuroanatomy, the cingulum or cingulum bundle is an association tract, a nerve tract that projects from the cingulate gyrus to the entorhinal cortex in the brain, allowing for communication between components of the limbic system. [1]
Research upon primates suggests that area 10 has inputs and output connections with other higher-order association cortex areas particularly in the prefrontal cortex while having few with primary sensory or motor areas. Its connections through the extreme capsule link it to the auditory and multisensory areas of the superior temporal sulcus.