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Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1 -antihistamine and it works by blocking certain effects of histamine , which produces its antihistamine and sedative effects.
First-generation antihistamines include diphenhydramine (Benadryl), carbinoxamine (Clistin), clemastine (Tavist), chlorpheniramine (Chlor-Trimeton), and brompheniramine (Dimetane). However, a 1955 study of "antihistaminic drugs for colds," carried out by the U.S. Army Medical Corps, reported that "there was no significant difference in the ...
Diphenhydramine is a first-generation antihistamine and an anticholinergic drug. Anticholinergic drugs block the action of acetylcholine, a neurotransmitter in the central nervous system. [13] Studies propose that long-term use of anticholinergic drugs is associated with an increased risk for dementia among older people.
Similarly, they suggest that those who are at risk of glaucoma should follow a special eye exam schedule: Ages 40 to 54: every one to three years. Ages 55 to 64: every one to two years.
Effects of anticholinergic drugs include: Delirium (often with hallucinations and delusions indistinguishable from reality); Ocular symptoms (from eye drops): mydriasis, pupil dilation, and acute angle-closure glaucoma in those with shallow anterior chamber [11] [12] [13]
Glaucoma medication is divided into groups based on chemical structure and pharmacologic action. The goal of currently available glaucoma therapy is to preserve visual function by lowering intraocular pressure (IOP) in patients that have an increased intraocular pressure.
Positive family history is a risk factor for glaucoma. The relative risk of having primary open-angle glaucoma is increased about two- to four-fold for people who have a sibling with glaucoma. [28] Glaucoma, particularly primary open-angle glaucoma, is associated with mutations in several genes, including MYOC, ASB10, WDR36, NTF4, TBK1, [29 ...
This isn’t the first time that better sleep has been linked with a lower risk of dementia: A study published in October even found that people with sleep apnea are more likely to develop dementia.
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