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Glaucoma medication is divided into groups based on chemical structure and pharmacologic action. The goal of currently available glaucoma therapy is to preserve visual function by lowering intraocular pressure (IOP) in patients that have an increased intraocular pressure.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, fever, and inflammation. [8] This includes painful menstrual periods, migraines, and rheumatoid arthritis. [8] It may also be used to close a patent ductus arteriosus in a premature baby. [9] [8] It can be taken orally (by mouth) or intravenously. [8]
Glaucoma can affect anyone. Some people have a higher risk or susceptibility to develop glaucoma due to certain risk factors, including increasing age, high intraocular pressure, a family history of glaucoma, and use of steroid medications. [1]
“Glaucoma is a highly familial disease, so premature and irreversible vision loss can affect multiple family members, contributing both to adverse health and economic outcomes,” Salowe added.
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Reversible acetylcholinesterase inhibitor agents such as physostigmine can be used as an antidote in life-threatening cases. Wider use is discouraged due to the significant side effects related to cholinergic excess including seizures, muscle weakness, bradycardia, bronchoconstriction, lacrimation, salivation, bronchorrhea, vomiting, and diarrhea.
Common side effects include dizziness and headaches. [7] Serious side effects may include allergic reactions, electrolyte abnormalities, and glaucoma. [2] Use in pregnancy is not recommended. [2] The combination was approved for medical use in the United States in 1998. [7] It is available as a generic medication. [6]
Ocular hypertension is the presence of elevated fluid pressure inside the eye (intraocular pressure), usually with no optic nerve damage or visual field loss. [1] [2]For most individuals, the normal range of intraocular pressure is between 10 mmHg and 21 mmHg. [3]
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