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  2. Endoplasmic reticulum - Wikipedia

    en.wikipedia.org/wiki/Endoplasmic_reticulum

    The endoplasmic reticulum (ER) is a part of a transportation system of the eukaryotic cell, and has many other important functions such as protein folding. It is a type of organelle made up of two subunits – rough endoplasmic reticulum (RER), and smooth endoplasmic reticulum (SER).

  3. Endomembrane system - Wikipedia

    en.wikipedia.org/wiki/Endomembrane_system

    There are two distinct, though connected, regions of ER that differ in structure and function: smooth ER and rough ER. The rough endoplasmic reticulum is so named because the cytoplasmic surface is covered with ribosomes, giving it a bumpy appearance when viewed through an electron microscope. The smooth ER appears smooth since its cytoplasmic ...

  4. Yop1p - Wikipedia

    en.wikipedia.org/wiki/Yop1p

    Thus, the peripheral ER is composed of a polygonal network of tubules and interdispersed sheets that spreads from the nuclear envelope to the cell cortex. At an ultrastructural level, the ER can be classified into two types, rough ER (RER) and smooth ER (SER). The RER has a sheet-like morphology and its main feature is the presence of ribosomes ...

  5. Membrane bound polyribosome - Wikipedia

    en.wikipedia.org/wiki/Membrane_bound_polyribosome

    The rough endoplasmic reticulum branches off of the cell nucleus, has multiple cisternae or layered folds that have interstitial space for protein extrusion. [3] Ribosomes are located in both the cytosol, cellular fluid, or rough endoplasmic reticulum and attach to this ribonucleic acid by separation and re-association of subunits around the ...

  6. Membrane contact site - Wikipedia

    en.wikipedia.org/wiki/Membrane_contact_site

    [3] [4] MCS are important in the function of the endoplasmic reticulum (ER), [5] since this is the major site of lipid synthesis within cells. [6] The ER makes close contact with many organelles, including mitochondria, Golgi, endosomes, lysosomes, peroxisomes, chloroplasts and the plasma membrane. [7]

  7. TRAPP complex - Wikipedia

    en.wikipedia.org/wiki/TRAPP_complex

    Proteins that are destined for the plasma membrane or export to the extracellular environment in eukaryotic cells are translated on ribosomes that sit on the rough endoplasmic reticulum (RER). Most proteins are co-translationally transported into the ER (i.e., while the ribosome is translating the mRNA code into a polypeptide , the polypeptide ...

  8. Microsome - Wikipedia

    en.wikipedia.org/wiki/Microsome

    Rough (containing ribosomes) and smooth (without ribosomes) microsomes are made from the endoplasmic reticulum through cell disruption. These microsomes have an inside that is exactly the same as the endoplasmic reticulum lumen. Both forms of microsomes can be purified by a process known as equilibrium density centrifugation. Rough and smooth ...

  9. Cellular compartment - Wikipedia

    en.wikipedia.org/wiki/Cellular_compartment

    The nucleolus within the nuclear envelope is the location of ribosome synthesis. The destination of synthesized ribosomes for protein translation is rough endoplasmic reticulum (rough ER), which is connected to and shares the same membrane with the nucleus. The Golgi body is also near the rough ER for packaging and redistributing. Likewise ...