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U.S. Route 45 crosses the Ohio River between Kentucky and Illinois on the Brookport Bridge. U.S. 45 enters Kentucky at Fulton then northeast past Mayfield then heads directly north into Paducah as a four-lane highway. In Paducah, U.S. 45 serves as a major artery, intersecting with Interstate 24 at exit 7, and intersecting US 60 and 62.
From the Mississippi state line, US 45 extends north as a four-lane divided highway, running concurrently with unsigned State Route 5 (SR 5), to an intersection with Old US Highway 45 S (a connector to Mississippi Highway 145 [MS 145]), where it narrows to an undivided four-lane and passes through the town of Guys.
SR 45 makes up much of the northern half of Nashville's Old Hickory Boulevard loop. It continues the loop from the intersection with Whites Creek Pike ( US 431 ) in Whites Creek . Traveling parallel to Little Creek , it enters Nashville proper and continues past I-24 exit 40 to its intersection with US 31W / US 41 (Dickerson Pike).
In the U.S. state of Alabama, U.S. Route 45 (US 45) is a 60-mile-long (97 km) north–south United States Highway in the east south central state of Alabama. It travels from Mobile to the Mississippi state line, just east of State Line, Mississippi. The highway's southern terminus is in Mobile, at an intersection with US 98. Its northern ...
The extension, which has been debated since 2018, involves a proposed 6.78 miles of new road that will cost an approximately $182 million.
U.S. Highway 45 (US 45) runs north–south through the eastern and northern portions of the state of Wisconsin.Also called Highway 45, it runs from the state line with Illinois near the village of Bristol in Kenosha County to the Michigan state line at the town of Land O' Lakes in Vilas County, a total of about 305 miles (491 km).
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U.S. Route 45 (US 45) in the state of Illinois is a major north–south U.S. Highway that runs from the Brookport Bridge over the Ohio River at Brookport north through rural sections of eastern Illinois and then through the suburbs of Chicago to the Wisconsin state line east of Antioch.