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  2. David A. Sinclair - Wikipedia

    en.wikipedia.org/wiki/David_A._Sinclair

    David Andrew Sinclair AO (born June 26, 1969) is an Australian-American biologist and academic known for his research on aging and epigenetics. Sinclair is a professor of genetics at Harvard Medical School and the founding director of the Paul F. Glenn Laboratories for the Biological Mechanisms of Aging at Harvard.

  3. Sirtris Pharmaceuticals - Wikipedia

    en.wikipedia.org/wiki/Sirtris_Pharmaceuticals

    Sirtris Pharmaceuticals, Inc. was a biotechnology company based in Cambridge, MA that developed therapies for type 2 diabetes, cancer, and other diseases. Conceived in 2004 by Harvard University biologist David Sinclair and Andrew Perlman, [1] and founded that year by Sinclair and Perlman, along with Christoph Westphal, Richard Aldrich, Richard Pops, and Paul Schimmel, [2] the company was ...

  4. Leonard P. Guarente - Wikipedia

    en.wikipedia.org/wiki/Leonard_P._Guarente

    In 1991 his lab started to study genes involved in aging. [5] In 1993, Cynthia Kenyon 's lab at UCSF discovered that a single-gene mutation in ( Daf-2 ) could double the lifespan of C. elegans . That same year, David Sinclair joined the Guarente lab, and they developed the hypothesis that caloric restriction slows aging by activation of ...

  5. Resveratrol - Wikipedia

    en.wikipedia.org/wiki/Resveratrol

    [53] [57] [58] [59] In 2004, Harvard University professor David Sinclair co-founded Sirtris Pharmaceuticals, the initial product of which was a resveratrol formulation. [60] [61] [62] Sirtris was purchased and made a subsidiary of GlaxoSmithKline in 2008 for $720 million and shut down in 2013, without successful drug development. [63] [64]

  6. Diabetes rates have quadrupled since 1990 — these are the 4 ...

    www.aol.com/news/diabetes-rates-quadrupled-since...

    The number of people living with diabetes worldwide has quadrupled in the past two decades, with 830 million people diagnosed as of 2022. Experts weigh in on the risk.

  7. The 6 Best Canned Soups for Better Blood Sugar ... - AOL

    www.aol.com/6-best-canned-soups-better-110000023...

    The carbs tend to be reasonable at around one serving of carbs (or around 15 grams), making it work into a balanced blood sugar meal plan,” says Toby Amidor, M.S., RD, author of Health Shots ...

  8. Demi Moore admits she thought “Ghost” might be a 'f---ing ...

    www.aol.com/demi-moore-admits-she-thought...

    "It had so many different genres mixed together that, truly, I thought, 'This could either be amazing or a f---ing disaster,'" Moore said of Ghost. "Either way, it's usually the kind of juice that ...

  9. Timeline of aging research - Wikipedia

    en.wikipedia.org/wiki/Timeline_of_aging_research

    In January, a team led by David Sinclair shows in a 13-year-long international study how DNA breaks or epigenetic damage are a major driver of epigenetic change, and how the loss of epigenetic information is a cause of aging in mammals. It concluded that the loss of epigenetic information can drive aging independently of changes to the genetic ...