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For example, aspirin, paracetamol, and caffeine are formulated together to treat pain caused by tension headaches and migraine. Additive effect can be used to detect synergy as it can be considered as the baseline effect in methods determining whether drugs have synergistic effect.
Antibiotic synergy is desirable in a clinic sense for several reasons. At the patient level, the boosted antimicrobial potency provided by synergy allows the body to more rapidly clear infections, resulting in shorter courses of antibiotic therapy. [3] Shorter courses of therapy in turn reduce the effects of dose-related toxicity, if applicable ...
Let and be doses of compounds 1 and 2 producing in combination an effect .We denote by and the doses of compounds 1 and 2 required to produce effect alone (assuming this conditions uniquely define them, i.e. that the individual dose-response functions are bijective).
Microbial synergy is a phenomenon in which aerobic and anaerobic microbes support each other's growth and proliferation. In this process aerobes invade and destroy host tissues, reduce tissue oxygen concentration and redox potential , thus creating favorable conditions for anaerobic growth and proliferation.
Agonist vs. antagonist. In pharmacology the term agonist-antagonist or mixed agonist/antagonist is used to refer to a drug which under some conditions behaves as an agonist (a substance that fully activates the receptor that it binds to) while under other conditions, behaves as an antagonist (a substance that binds to a receptor but does not activate and can block the activity of other agonists).
The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology , being itself a topic of biology interested in the study of the interactions of both endogenous and exogenous chemical ...
Pentagon officials are holding informal discussions about how the Department of Defense would respond if Donald Trump issues orders to deploy active-duty troops domestically and fire large swaths ...
The Compendium of Pharmaceuticals and Specialties: The Canadian Drug Reference for Health Professionals, more commonly known by its abbreviation CPS, [1] is a reference book that contains drug monographs and numerous features which help healthcare professionals prescribe and use drugs safely and appropriately.