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2. Luria–Delbrück experiment - Wikipedia

   en.wikipedia.org/wiki/Luria–Delbrück_experiment

   Luria–Delbrück experiment. The two possibilities tested by the Luria–Delbrück experiment. (A) If mutations are induced by the media, roughly the same number of mutants are expected to appear on each plate. (B) If mutations arise spontaneously during cell divisions prior to plating, each plate will have a highly variable number of mutants.

3. BRCA1 - Wikipedia

   en.wikipedia.org/wiki/BRCA1

   BRCA1 serine cluster domain (SCD) spans amino acids 1280–1524. A portion of the domain is located in exons 11–13. High rates of mutation occur in exons 11–13. Reported phosphorylation sites of BRCA1 are concentrated in the SCD, where they are phosphorylated by ATM/ATR kinases both in vitro and in vivo.

4. Somatic mutation - Wikipedia

   en.wikipedia.org/wiki/Somatic_mutation

   Somatic mutation. A somatic mutation is a change in the DNA sequence of a somatic cell of a multicellular organism with dedicated reproductive cells; that is, any mutation that occurs in a cell other than a gamete, germ cell, or gametocyte. Unlike germline mutations, which can be passed on to the descendants of an organism, somatic mutations ...

5. Horizontal gene transfer - Wikipedia

   en.wikipedia.org/wiki/Horizontal_gene_transfer

   Horizontal gene transfer (HGT) or lateral gene transfer (LGT) [ 1 ][ 2 ][ 3 ] is the movement of genetic material between organisms other than by the ("vertical") transmission of DNA from parent to offspring (reproduction). [ 4 ] HGT is an important factor in the evolution of many organisms. [ 5 ][ 6 ] HGT is influencing scientific ...

6. One gene–one enzyme hypothesis - Wikipedia

   en.wikipedia.org/wiki/One_gene–one_enzyme...

   The one gene–one enzyme hypothesis is the idea that genes act through the production of enzymes, with each gene responsible for producing a single enzyme that in turn affects a single step in a metabolic pathway. The concept was proposed by George Beadle and Edward Tatum in an influential 1941 paper [1] on genetic mutations in the mold ...

7. Mutation - Wikipedia

   en.wikipedia.org/wiki/Mutation

   Suppressor mutations are a type of mutation that causes the double mutation to appear normally. In suppressor mutations the phenotypic activity of a different mutation is completely suppressed, thus causing the double mutation to look normal. There are two types of suppressor mutations, there are intragenic and extragenic suppressor mutations ...

8. Genetic engineering - Wikipedia

   en.wikipedia.org/wiki/Genetic_engineering

   This is an accepted version of this page This is the latest accepted revision, reviewed on 14 October 2024. Manipulation of an organism's genome For a non-technical introduction to the topic of genetics, see Introduction to genetics. For the song by Orchestral Manoeuvres in the Dark, see Genetic Engineering (song). For the Montreal hardcore band, see Genetic Control. Part of a series on ...

9. Genetic transformation - Wikipedia

   en.wikipedia.org/wiki/Genetic_transformation

   In this image, a gene from one bacterial cell is moved to another bacterial cell. This process of the second bacterial cell taking up new genetic material is called transformation. In molecular biology and genetics, transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic ...