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Anticonvulsant. Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. [1] Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [2][3] and borderline personality disorder ...
Epilepsy is a neurological condition of recurrent episodes of unprovoked epileptic seizures. A seizure is an abnormal neuronal brain activity that can cause intellectual, emotional, and social consequences. Epilepsy affects children and adults of all ages and races, and is one of the most common neurological disorders of the nervous system. [ 1 ]
A neonatal seizure is a seizure in a baby younger than age 4-weeks that is identifiable by an electrical recording of the brain. [1] It is an occurrence of abnormal, paroxysmal, and persistent ictal rhythm with an amplitude of 2 microvolts in the electroencephalogram,. [2] These may be manifested in form of stiffening or jerking of limbs or trunk.
140,000 (2021) [ 9 ] Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. [ 10 ] An epileptic seizure is the clinical manifestation of an abnormal, excessive, and synchronized electrical discharge in the neurons. [ 1 ] The occurrence of two or more unprovoked seizures defines epilepsy. [ 11 ]
Levetiracetam. Levetiracetam, sold under the brand name Keppra among others, is a medication used to treat epilepsy. [ 7 ] It is used for partial-onset, myoclonic, or tonic–clonic seizures and is taken either by mouth as an immediate or extended release formulation or by injection into a vein. [ 7 ]
Benzodiazepines developed in the former Soviet Union (e.g. phenazepam, gidazepam etc.) Benzodiazepines predominantly used only in Japan (e.g. nimetazepam, flutoprazepam etc.) 4,5-cyclised benzodiazepines (e.g. ketazolam, cloxazolam etc.), and other compounds not researched by Roche.
Topiramate, sold under the brand name Topamax among others, is a medication used to treat epilepsy and prevent migraines. [ 9 ] It has also been used in alcohol dependence and essential tremor. [ 9 ] For epilepsy this includes treatment for generalized or focal seizures. [ 10 ] It is taken orally (by mouth).
Phenytoin (PHT), sold under the brand name Dilantin among others, [ 1 ] is an anti-seizure medication. [ 3 ] It is useful for the prevention of tonic-clonic seizures (also known as grand mal seizures) and focal seizures, but not absence seizures. [ 3 ]