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It uses a range of grades from 1 to 5. Specific conditions and symptoms may have values or descriptive comment for each level, but the general guideline is: 1 - Mild 2 - Moderate 3 - Severe 4 - Life-threatening 5 - Death. Grade 1: is defined as mild, asymptomatic symptoms. Clinical or diagnostic observations only; Intervention not indicated.
The IACC Strategic Plan was designed to detail research opportunities centered on the six most pressing questions facing those affected by autism and links them to specific research efforts. In 2009, the plan was finalized and submitted to the Secretary of the Department of Health and Human Services; a seventh question related to infrastructure ...
Research has revealed that neural progenitor cells are particularly vulnerable to the cytotoxic effects of chemotherapy agents. 5-fluorouracil has been demonstrated to reduce the viability of neural progenitor cells by 55–70% at concentrations of 1 μM, whereas cancer cell lines exposed to 1 μM of 5-fluorouracil were unaffected. [ 24 ]
Autism Research is a bimonthly peer-reviewed medical journal covering research on autism and other pervasive developmental disorders. It was established in 2008 and is the official journal of the International Society for Autism Research. It is published bimonthly by Wiley-Blackwell. The editor-in-chief is David G. Amaral (University of ...
This is a list of chemotherapeutic agents, also known as cytotoxic agents or cytostatic drugs, that are known to be of use in chemotherapy for cancer.This list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.
Research in Autism Spectrum Disorders is a peer-reviewed medical journal published monthly by Elsevier. It covers applied topics pertaining to autism spectrum disorders. Since the spring of 2023, the editor-in-chief is David Beversdorf (University of Missouri). According to the Journal Citation Reports, in 2012 the journal had an impact factor ...
Bone marrow suppression is a serious side effect of chemotherapy and certain drugs affecting the immune system such as azathioprine. [2] The risk is especially high in cytotoxic chemotherapy for leukemia. In the case of non-small-cell lung cancer, myelosuppression predisposition was shown to be modulated by enhancer mutations. [3]
A label-free approach to follow the cytotoxic response of adherent animal cells in real-time is based on electric impedance measurements when the cells are grown on gold-film electrodes. This technology is referred to as electric cell-substrate impedance sensing (ECIS). Label-free real-time techniques provide the kinetics of the cytotoxic ...