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Polyvinylpyrrolidone (PVP), also commonly called polyvidone or povidone, is a water-soluble polymer compound made from the monomer N-vinylpyrrolidone. [1] PVP is available in a range of molecular weights and related viscosities, and can be selected according to the desired application properties.
In photothermal cancer therapy, many gold nanoparticle molecules are used in each test and they must all be uniform in size. Including PEG coating, the nanoparticles measured to be ~130 nm in diameter. [1] Gold nanoparticles that act as drug delivery systems in conjugation with chemotherapeutic drugs typically range in size from 10 to 100 nm. [2]
Experimental cancer treatments are normally available only to people who participate in formal research programs, which are called clinical trials. Occasionally, a seriously ill person may be able to access an experimental drug through an expanded access program. Some of the treatments have regulatory approval for treating other conditions.
Multidrug resistance in cancer cells is thought to be the primary reason for the poor efficacy of cancer chemotherapy. Drug resistance is due to expression of the gene MDR-1. These gene codes for membrane-bound proteins called ABC transporters. One example of an ABC transporter is P-glycoprotein (P-gp).
The Mercury Drug Corporation, better known as Mercury Drug, is a Filipino pharmacy chain. A subsidiary of the Mercury Group of Companies, it is headquartered in Bagumbayan, Quezon City . [ 5 ] The chain was founded in Santa Cruz, Manila in 1945, [ 1 ] making it the second oldest drugstore chain in the Philippines after Southstar Drug by eight ...
It can be directed to the location of cancer cells with sustained release behavior. Studies have also been done on gold nanoparticle responses to local near-infrared (NIR) light as a stimuli for drug release. In one study, gold nanoparticles functionalized with double-stranded DNA encapsulated with drug molecules, were irradiated with NIR light.
Nanomedicine is the medical application of nanotechnology. [1] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines.
α-Pyrrolidinopentiophenone (α-PVP), also known as α-pyrrolidinovalerophenone, O-2387, β-keto-prolintane, prolintanone, [2] [3] or desmethylpyrovalerone, is a synthetic stimulant of the cathinone class developed in the 1960s that has been sold as a designer drug and often consumed for recreational reasons.