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Treatment of hepatocellular carcinoma varies by the stage of disease, a person's likelihood to tolerate surgery, and availability of liver transplantation: Curative intention: for limited disease, when the cancer is limited to one or more areas of within the liver, surgically removing the malignant cells may be curative.
Viral infection with hepatitis C virus (HCV) or Hepatitis B virus (HBV) is the chief cause of liver cancer in the world today, accounting for 80% of HCC. [ 28 ] [ 29 ] [ 30 ] Men with chronic HCV or HBV are more likely to develop HCC than women with chronic HCV or HBV; however, the reasons for this gender difference is unknown.
The hepatitis C virus (HCV), in species Hepacivirus C, infects humans and is associated with hepatitis and hepatocellular carcinoma. [ 3 ] [ 4 ] There are fourteen species in the genus which infect a range of other vertebrate .
This type of infection dramatically increases the incidence of hepatocellular carcinoma (HCC; liver cancer). Across Europe, hepatitis B and C cause approximately 50% of hepatocellular carcinomas. [22] [23] Chronic carriers are encouraged to avoid consuming alcohol as it increases their risk for cirrhosis and liver cancer. Hepatitis B virus has ...
[7] [8] One of the major challenges in cancer treatment is finding treatments that target tumor cells while ignoring non-cancerous host cells. Viruses are chosen because they can target specific receptors expressed by cancer cells that allow for virus entry. One example of this is the targeting of CD46 on multiple myeloma cells by measles virus ...
The treatment of chronic liver disease depends on the cause. Specific conditions may be treated with medications including corticosteroids , interferon , antivirals , bile acids or other drugs. Supportive therapy for complications of cirrhosis include diuretics , albumin , vitamin K , blood products , antibiotics and nutritional therapy.
Fibrolamellar carcinoma (FLC) is a rare form of carcinoma that typically affects young adults and is characterized, under the microscope, by laminated fibrous layers interspersed between the tumor cells. [1] It has been estimated that 200 new cases are diagnosed worldwide each year. [2]
The goal of treatment is prevention of hepatocellular carcinoma (HCC). [111] The best way to reduce the long-term risk of HCC is to achieve sustained virological response (SVR). [ 111 ] SVR is defined as an undetectable viral load at 12 weeks after treatment completion and indicates a cure.