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Plasmapheresis (from the Greek πλάσμα, plasma, something molded, and ἀφαίρεσις aphairesis, taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation. It is thus an extracorporeal therapy, a medical procedure performed outside the body. [1]
The exchange transfusion is done in cycles: each one usually lasts a few minutes. [1] The patient’s blood is slowly withdrawn (usually about 5 to 20 mL at a time, depending on the patient’s size and the severity of illness), and a slightly larger amount of fresh, prewarmed blood or plasma flows into the patient's body.
Plasmapheresis – blood plasma. Plasmapheresis is useful in collecting FFP (fresh frozen plasma) of a particular ABO group. Commercial uses aside from FFP for this procedure include immunoglobulin products, plasma derivatives, and collection of rare WBC and RBC antibodies. A Fenwal Erythropheresis machine being used for plasmapheresis
Blood plasma has a density of approximately 1,025 kg/m 3 (1.025 g/ml). [8] Blood serum is blood plasma without clotting factors. [5] Plasmapheresis is a medical therapy that involves blood plasma extraction, treatment, and reintegration.
Understand the different processes before you decide to give.
1) Plasma exchange is not synonymous with plasmapheresis. As it is implied in the article this procedure can be used for donation of plasma therefore nothing is exchanged also it can be used for removal of the plasma and replacing it with other fluids, usually Normal Saline or Albumin rather than Plasma. This latter process is called Plasma ...
Plasma exchange (or plasmapheresis), the removal of plasma proteins such as antibodies and replacement with normal plasma, may provide improvement in acute severe weakness. Plasma exchange is less effective than in other related conditions such as myasthenia gravis, and additional immunosuppressive medication is often needed.
In most cases, blood plasma is returned to the donor as well. However, in locations that have plasma processing facilities, a part of the donor's plasma can also be collected in a separate blood bag (see plasmapheresis). For example, in Australia around 5.9×10 11 platelets and 580 mL of plasma might be collected from an 88 kg donor.