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¯ = sample mean of differences d 0 {\displaystyle d_{0}} = hypothesized population mean difference s d {\displaystyle s_{d}} = standard deviation of differences
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Sample size determination or estimation is the act of choosing the number of observations or replicates to include in a statistical sample. The sample size is an important feature of any empirical study in which the goal is to make inferences about a population from a sample.
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