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These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Tends to produce less extrapyramidal side effects than typical antipsychotics but more extrapyramidal side effects than sertindole, clozapine and quetiapine. [9] [10] Mild and transient constipation and xerostomia (dry mouth) [citation needed] Dizziness [citation needed] Weight gain of over 15% of one's initial body weight.
Nervousness; Insomnia; Sleep disorder; Disturbance in attention; Depression; Confusional state; Anger; Tachycardia (fast heart rate); Chest pain; Sinusitis (nasal ...
These agents are associated with fewer neuromotor side effects and a lower risk of developing tardive dyskinesia. [ 37 ] Studies have tested the use of melatonin , high dosage vitamins , and different antioxidants in concurrence with antipsychotic drugs (often used to treat schizophrenia ) as a way of preventing and treating tardive dyskinesia.
Aripiprazole is an effective add-on treatment for major depressive disorder; however, there is a greater rate of side effects such as weight gain and movement disorders. [ 37 ] [ 38 ] [ 39 ] The overall benefit is small to moderate and its use appears to neither improve quality of life nor functioning. [ 37 ]
Note: "Notable" is to mean side-effects that are particularly unique to the antipsychotic drug in question. For example, clozapine is notorious for its ability to cause agranulocytosis. If data on the propensity of a particular drug to cause a particular AE is unavailable an estimation is substituted based on the pharmacologic profile of the drug.
Some children have a habit of sucking and chewing on the lower lip, producing a combination of cheilitis and a sharply demarcated perioral erythema. [2] Treatment is usually successful with barrier lubricants, such as lip salve or Vaseline. [5] Medical grade lanolin accelerates repair of the lips, [9] and is used in some lip repair products.
The side-effects profile varies for different patient populations. [51] Overall adverse effects in treatment are similar between men, women, geriatric, pediatric, and racial groups. [5] Lamotrigine has been associated with a decrease in white blood cell count . [54] Lamotrigine does not prolong QT/QTc in TQT studies in healthy subjects. [55]