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Summation, which includes both spatial summation and temporal summation, is the process that determines whether or not an action potential will be generated by the combined effects of excitatory and inhibitory signals, both from multiple simultaneous inputs (spatial summation), and from repeated inputs (temporal summation).
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The two ways that synaptic potentials can add up to potentially form an action potential are spatial summation and temporal summation. [5] Spatial summation refers to several excitatory stimuli from different synapses converging on the same postsynaptic neuron at the same time to reach the threshold needed to reach an action potential.
Temporal summation means that the effects of impulses received at the same place can add up if the impulses are received in close temporal succession. Thus the neuron may fire when multiple impulses are received, even if each impulse on its own would not be sufficient to cause firing.
Electrotonic potentials can sum spatially or temporally. Spatial summation is the combination of multiple sources of ion influx (multiple channels within a dendrite, or channels within multiple dendrites), whereas temporal summation is a gradual increase in overall charge due to repeated influxes in the same location. Because the ionic charge ...
In classic brain theory the summation of electrical inputs to the dendrites and soma (cell body) of a neuron either inhibit the neuron or excite it and set off an action potential down the axon to where it synapses with the next neuron. However, this fails to account for different varieties of synapses beyond the traditional axodendritic (axon ...
[1] According to temporal summation one would expect the inhibitory and excitatory currents to be summed linearly to describe the resulting current entering the cell. However, when inhibitory and excitatory currents are on the soma of the cell, the inhibitory current causes the cell resistance to change (making the cell "leakier"), thereby ...
Download as PDF; Printable version; ... Summation may also refer to: Addition; Summation (neurophysiology), a way of achieving action potential in a neuron; In law, ...