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Cypermethrin is very toxic to cats which cannot tolerate the therapeutic doses for dogs. [6] This is associated with UGT1A6 deficiency in cats, the enzyme responsible for metabolizing cypermethrin. As a consequence, cypermethrin remains much longer in the cat's organs than in dogs or other mammals and can be fatal in large doses.
Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8]It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
Contemporary commercial products for the topical treatment of flea infestations on pets contain pesticides such as imidacloprid, permethrin, and (S)-methoprene. All flea-control products are recommended to be used at least half-yearly because the lifecycle of flea can last up to a year. [ 5 ]
It is effective against fleas, ticks, chewing lice and mosquitoes. [1] The active ingredients are imidacloprid, permethrin, and pyriproxyfen. This product is toxic to cats, [2] and it is not recommended to use it on dogs which share an environment with cats. [1]
Tick paralysis is believed to be due to toxins found in the tick's saliva that enter the bloodstream while the tick is feeding. The two ticks most commonly associated with North American tick paralysis are the Rocky Mountain wood tick (Dermacentor andersoni) and the American dog tick (Dermacentor variabilis); however, 43 tick species have been implicated in human disease around the world. [1]
Chemical structure of permethrin, a common acaricide.. Acaricides are pesticides that kill members of the arachnid subclass Acari, which includes ticks and mites.Acaricides are used both in medicine and agriculture, although the desired selective toxicity differs between the two fields.
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