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Bronchiolitis obliterans when it occurs following a lung transplant is known as bronchiolitis obliterans syndrome (BOS). [11] [4] BOS is defined as a person who has had either a HSCT or lung transplant and develops symptoms or radiographic findings consistent with bronchiolitis obliterans, but has not been confirmed by biopsy. [22] [20]
Cryptogenic organizing pneumonia (COP), formerly known as bronchiolitis obliterans organizing pneumonia (BOOP), is an inflammation of the bronchioles (bronchiolitis) and surrounding tissue in the lungs. [2] [3] It is a form of idiopathic interstitial pneumonia. [4]
[5] [6] Often when people refer to bronchiolitis, they are referring to acute bronchiolitis in children. [5] Acute bronchiolitis is usually the result of viral infection by respiratory syncytial virus (RSV) (59.2% of cases) or human rhinovirus (19.3% of cases). [7] Diagnosis is generally based on symptoms. [1]
Typical symptoms are of recurrent respiratory tract infections, but some have no symptoms. [2] As a result of childhood bronchiolitis obliterans, typically following adenovirus infection, there is a reduction in blood vessels and overextended alveoli, resulting in air trapping in one or part of one lung. [1]
Lower respiratory infectious disease is the fifth-leading cause of death and the combined leading infectious cause of death, being responsible for 2.74 million deaths worldwide. [27] This is generally similar to estimates in the 2010 Global Burden of Disease study. [ 28 ]
Bronchiolitis obliterans, also known as constrictive bronchiolitis or obliterative bronchiolitis is a respiratory disease caused by injury to the smallest airways, called bronchioles. It has been reported to occur from exposure to inhaled toxins and gases including sulfur mustard gas, nitrogen oxides, diacetyl (used in many food and beverage ...
DPB is classified as a form of "primary bronchiolitis", which means that the underlying cause of bronchiolitis is originating from or is confined to the bronchioles. [ 2 ] [ 3 ] Along with DPB, additional forms of primary bronchiolitis include bronchiolitis obliterans , follicular bronchiolitis, respiratory bronchiolitis , mineral dust airway ...
A history of exposure to potential causes and evaluation of symptoms may help in revealing the cause the exacerbation, which helps in choosing the best treatment. A sputum culture can specify which strain is causing a bacterial AECB. [5] An early morning sample is preferred. [7] E-nose showed the ability to smell the cause of the exacerbation. [8]