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Entamoeba histolytica in peripheral blood Life-cycle of Entamoeba histolytica. Entamoeba histolytica is an anaerobic parasitic amoebozoan, part of the genus Entamoeba. [1] Predominantly infecting humans and other primates causing amoebiasis, E. histolytica is estimated to infect about 35-50 million people worldwide. [1] E. histolytica infection ...
In 2017, auranofin completed phase I clinical trials against Entamoeba histolytica and Giardia [10] The Barrios Lab in the Department of Pharmacy at the University of Utah largely focuses on developing chemical probes to study biological substrates, substrate selectivity, cellular regulation, and druggability for use in therapeutics.
The genus Entamoeba was defined by Casagrandi and Barbagallo for the species Entamoeba coli, which is known to be a commensal organism. [2] Lösch's organism was renamed Entamoeba histolytica by Fritz Schaudinn in 1903; he later died, in 1906, from a self-inflicted infection when studying this amoeba.
Chromatoidal bodies are aggregations of ribosomes found in cysts of some amoebae including Entamoeba histolytica and Entamoeba coli. They exist in the cytoplasm and are dark staining. In the early cystic stages of E. histolytica, chromatid bodies arise from aggregation of ribosomes forming polycrystalline masses. As the cyst matures, the masses ...
The two most common manifestations of E histolytica include colitis (bloody stool with mucus, abdominal pain, and/or diarrhea), and discovery of a liver abscess on imaging. [2] Liver abscesses commonly present as right upper quadrant abdominal pain and fever, with worsening features associated with abscess rupture.
The choices being Entamoeba moshkovskii, Entamoeba histolytica, or Entamoeba dispar. These three choices are, in the view of the microscope, "indistinguishable". [1] This is the point where a doctor makes the call for what is most common (Entamoeba histolytica) or something more rare (Entamoeba mushkovskii).
Sudha Bhattacharya (born 7 March 1952) is an Indian academic, scientist and a writer. She is recognized primarily for her in-depth study of Entamoeba histolytica, a parasitic protozoan that causes amoebiasis: Dr. Bhattacharya's laboratory first detected Ribosomal RNA genes on Circular DNA, while studying the parasite, and also discovered families of retrotransposons in the parasite genome. [1]
In 2004 El Hamshary and Arafa found that salivary anti-E. histolytica IgA concentration had "predictive diagnostic value of intestinal amoebiasis…as well as in tissue amoebiasis." [61] A 1990 study that involved saliva testing for E. histolytica in 223 school children demonstrated a sensitivity and specificity of 85% and 98%, respectively. [62]