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Spinal muscular atrophy (SMA) is a rare neuromuscular disorder that results in the loss of motor neurons and progressive muscle wasting. [3] [4] [5] It is usually diagnosed in infancy or early childhood and if left untreated it is the most common genetic cause of infant death. [6]
The Singapore Medical Association (abbreviated SMA) is a professional association representing the interests of medical professionals in Singapore. It was established on September 15, 1959, replacing the Malaya Branch of the British Medical Association. [2] As of 2020, it had over 8,200 members. [3]
Spinal and bulbar muscular atrophy (SBMA), popularly known as Kennedy's disease, is a rare, adult-onset, X-linked recessive lower motor neuron disease caused by trinucleotide CAG repeat expansions in exon 1 of the androgen receptor (AR) gene, which results in both loss of AR function and toxic gain of function.
Deaths in Singapore offset the population increase from live births. In 2007, 17,140 people in Singapore died from various causes. The death rate was 4.5 deaths per 1,000 of the population. [1] There are strict regulations surrounding death and treatment of the body after death.
11q13.3: Autosomal recessive: Affects mainly infant boys, similar to SMA type 1 but with diaphragmatic paralysis Distal spinal muscular atrophy type 2 (DSMA2) Distal hereditary motor neuronopathy – Jerash type (DHMN-J) 605726: SIGMAR1: 19p13.3: Autosomal recessive: Slowly progressive Distal spinal muscular atrophy type 3 (DSMA3)
SMA syndrome is also known as Wilkie's syndrome, cast syndrome, mesenteric root syndrome, chronic duodenal ileus and intermittent arterio-mesenteric occlusion. [3] It is distinct from nutcracker syndrome , which is the entrapment of the left renal vein between the AA and the SMA, although it is possible to be diagnosed with both conditions.
The death of a 73-year-old British man on a Singapore Airlines flight has again raised concerns about how climate change is increasing instances of flight turbulence.
In 2000, Singapore was ranked 6th in the World Health Organization's ranking of the world's health systems. [1] Bloomberg ranked Singapore's healthcare system the most efficient in the world in 2014. [2] The Economist Intelligence Unit placed Singapore 2nd out of 166 countries for health-care outcomes. [3]