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Aspirin-exacerbated respiratory disease (AERD), also called NSAID-exacerbated respiratory disease (N-ERD) or historically aspirin-induced asthma and Samter's Triad, is a long-term disease defined by three simultaneous symptoms: asthma, chronic rhinosinusitis with nasal polyps, and intolerance of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs).
Asthma is a long-term inflammatory disease of the airways of the lungs. [4] It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. [9][10] Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. [3]
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [10] For pain or fever, effects typically begin within 30 minutes. [10] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [10] One common adverse effect is an upset ...
Max Samter. Max Samter (March 8, 1909 – February 9, 1999) was a German-American immunologist who first extensively studied the triad between asthma, aspirin allergy, and nasal polyps that became known as Samter's triad, now aspirin-exacerbated respiratory disease. [1] Samter was a third generation doctor and obtained medical training in ...
Aspirin helps thin the blood, which can prevent these blood clots from forming. That is why it had long been recommended to take a daily low-dose aspirin to reduce your risk. However, because ...
Acute severe asthma. Silent chest, worsening symptoms despite use of medication. [1] Acute severe asthma, also known as status asthmaticus, is an acute exacerbation of asthma that does not respond to standard treatments of bronchodilators (inhalers) and corticosteroids. [2] Asthma is caused by multiple genes, some having protective effect, with ...
Aspirin may also be used to lower the risk of a heart attack or stroke in people who have already had one, O’Mahony says. But that path is not without risk. “This medication can increase the ...
The prevalence of asthma increased 75% from 1980 to 1994. Asthma prevalence is 39% higher in African Americans than in Europeans. [126] 5.7 million (about 9.4%). In six- and seven-year-olds asthma increased from 18.4% to 20.9% over five years, during the same time the rate decreased from 31% to 24.7% in 13- to 14-year-olds. Atopic eczema