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  2. Exercise and antidepressants may be the most effective combo ...

    www.aol.com/finance/exercise-antidepressants-may...

    How exercise compares to antidepressants. Arguably the most interesting finding, though, is that the effect of exercise on depressed people appeared superior to antidepressants. Yet, when combined ...

  3. Neurobiological effects of physical exercise - Wikipedia

    en.wikipedia.org/wiki/Neurobiological_effects_of...

    Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...

  4. Serotonin–norepinephrine reuptake inhibitor - Wikipedia

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    Serotonin–norepinephrine reuptake inhibitors (SNRIs) are a class of antidepressant medications used to treat major depressive disorder (MDD), anxiety disorders, social phobia, chronic neuropathic pain, fibromyalgia syndrome (FMS), and menopausal symptoms. Off-label uses include treatments for attention-deficit hyperactivity disorder (ADHD ...

  5. Development and discovery of SSRI drugs - Wikipedia

    en.wikipedia.org/wiki/Development_and_discovery...

    Selective serotonin reuptake inhibitors, or serotonin-specific re-uptake inhibitor (SSRIs), are a class of chemical compounds that have application as antidepressants and in the treatment of depression and other psychiatric disorders. SSRIs are therapeutically useful in the treatment of panic disorder (PD), posttraumatic stress disorder (PTSD ...

  6. Has ketamine’s time of reckoning arrived? 5 things to know ...

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    Unlike traditional antidepressants that target the neurotransmitters serotonin and/or norepinephrine, ketamine targets glutamate — the most abundant chemical messenger in the brain, Feifel said ...

  7. Sertraline - Wikipedia

    en.wikipedia.org/wiki/Sertraline

    Sertraline, sold under the brand name Zoloft among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [ 10 ] The effectiveness of sertraline for depression is similar to that of other antidepressants, and the differences are mostly confined to side effects. Sertraline is better tolerated than the older ...

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