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Merkel cells (shown in blue) are located in the basal epidermal layer of the skin. Merkel cells, also known as Merkel–Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates. They are abundant in highly sensitive skin like that of the fingertips in ...
Tactile corpuscles or Meissner's corpuscles are a type of mechanoreceptor discovered by anatomist Georg Meissner (1829–1905) and Rudolf Wagner. [1][2] This corpuscle is a type of nerve ending in the skin that is responsible for sensitivity to pressure. In particular, they have their highest sensitivity (lowest threshold) when sensing ...
This photo shows tactile markings identifying stairs for visually impaired people. The somatosensory system, or somatic sensory system is a subset of the sensory nervous system. It has two subdivisions, one for the detection of mechanosensory information related to touch, and the other for the nociception detection of pain and temperature. [1]
Merkel cells transduce tactile stimuli / mechanical forces into excitatory signals, which trigger vesicular serotonin release; they have also been called a "serotonergic synapse". [2] They have similar functions as the enterochromaffin cell, the mechanosensory cell in the GI epithelium, [2] which synthesizes 95% of the body's total serotonin or ...
The dermis is composed of three major types of cells: [3] fibroblasts, macrophages, and mast cells.. Apart from these cells, the dermis is also composed of matrix components such as collagen (which provides strength), elastin (which provides elasticity), and extrafibrillar matrix, an extracellular gel-like substance primarily composed of glycosaminoglycans (most notably hyaluronan ...
The epidermis is composed of multiple layers of flattened cells [4] that overlie a base layer (stratum basale) composed of columnar cells arranged perpendicularly. The layers of cells develop from stem cells in the basal layer. The thickness of the epidermis varies from 31.2μm for the penis to 596.6μm for the sole of the foot with most being ...
The Pacinian corpuscle, lamellar corpuscle or Vater-Pacini corpuscle[1] is one of the four major types of cutaneous receptor a type of mechanoreceptor (specialized receptor for mechanical sensation) found in mammalian skin. This type of mechanoreceptor is found in both hairy, and hairless skin, organs, joints, and attached to the periosteum of ...
Keratinocyte. Keratinocytes are the primary type of cell found in the epidermis, the outermost layer of the skin. In humans, they constitute 90% of epidermal skin cells. [1] Basal cells in the basal layer (stratum basale) of the skin are sometimes referred to as basal keratinocytes. [2] Keratinocytes form a barrier against environmental damage ...