Search results
Results from the WOW.Com Content Network
[107] [123] [124] However, later studies by different researchers found the affinity of ketamine of >10 μM for the regular human and rat D 2 receptors, [102] [108] [109] Moreover, whereas D 2 receptor agonists such as bromocriptine are able to rapidly and powerfully suppress prolactin secretion, [125] subanesthetic doses of ketamine have not ...
The use of ketamine as part of a "post-clubbing experience" has also been documented. [36] Ketamine's rise in the dance culture was most rapid in Hong Kong by the end of the 1990s. [32] Ketamine use as a recreational drug has been implicated in deaths globally, with more than 90 deaths in England and Wales in the years of 2005–2013. [37]
Ketamine is a short-acting, noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. [2] It was discovered by Parke-Davis Labs and Dr. Calvin Lee Stevens in 1962 during research into derivatives of phencyclidine (PCP). [6] It was first used clinically as a veterinary anesthetic. The first dose of ketamine was administered to a human by ...
Ketamine can be a lifeline for certain people who have not responded to common treatments for depression, such as medications and different forms of psychotherapy.
Ketamine is a hallucinogen that was approved by the Food and Drug Administration as an anesthetic for surgery decades ago, but it’s also used illegally as a party drug. Over the last few years ...
A cause of death has been determined for Matthew Perry, months after the Friends star was found unresponsive in a hot tub at his home. Perry died due to the acute effects of ketamine, according to ...
In 1832 produced chloral hydrate, the first synthetic sleeping drug. In 1833 French chemist Anselme Payen was the first to discover an enzyme, diastase. In 1834, François Mothes and Joseph Dublanc created a method to produce a single-piece gelatin capsule that was sealed with a drop of gelatin solution.
[20] [21] A 2009 review found no evidence of ketamine-induced neuron death in humans. [22] However, temporary and permanent cognitive impairments have been shown to occur in long-term or heavy human users of the NMDA antagonists PCP and ketamine.