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There’s a very low risk the injections damage nerves, joints or other tissue near the injection site, but prolotherapy isn’t riskier than any other injection. Make sure you receive prolotherapy from a certified healthcare provider to minimize your chances of complications.
Prolotherapy seems to be a safe treatment based on the limited research. None of the clinical trials for prolotherapy and low back pain show any serious side effects. Mild effects may include:
Dextrose or saline prolotherapy involve injecting a sugar or salt solution into a joint or other part of the body to treat a range of conditions, such as: tendon, muscle, and ligament problems....
Prolotherapy appears to be a safe treatment alternative that has been shown to improve stiffness, pain, function, and quality of life in osteoarthritis of the knee. Knee osteoarthritis is remarkably prevalent in the United States and is one of the most common causes of disability in the elderly population.
Prolotherapy performed by an experienced practitioner is relatively safe. In rare cases, serious adverse events may occur when delicate neurological tissues of the spine are inadvertently injured or if the patient is allergic to one or more contents of the injection solution.
By injecting a solution of dextrose (a natural sugar chemically identical to the body's own glucose) prolotherapy providers aim to provide non-surgical healing for inflamed and damaged joints. Here's what you should know about the efficacy and risks of prolotherapy.
Learn all about prolotherapy, an alternative form of treatment for joint and back pain. We take a look at how it works, what to expect, and its efficacy.