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  2. Non-mevalonate pathway - Wikipedia

    en.wikipedia.org/wiki/Non-mevalonate_pathway

    Non-mevalonate pathway reactions in the biosynthesis of isoprenoids. Redrawn verbatim from the scheme of Qidwai and coworkers [Fig. 2.]. [9] Note, the enzyme abbreviations in this figure are non-standard (cf. Eisenreich et al. [10]), but are presented here and reproduced in the table to allow the two sets of data to be used together.

  3. 4-Diphosphocytidyl-2-C-methylerythritol - Wikipedia

    en.wikipedia.org/wiki/4-diphosphocytidyl-2-C...

    4-Diphosphocytidyl-2-C-methylerythritol (or CDP-ME) is an intermediate in the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis. It is produced by the enzyme 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase (IspD) and is a substrate for CDP-ME kinase (IspE)

  4. Isopentenyl pyrophosphate - Wikipedia

    en.wikipedia.org/wiki/Isopentenyl_pyrophosphate

    Isopentenyl pyrophosphate (IPP, isopentenyl diphosphate, or IDP) [1] is an isoprenoid precursor. IPP is an intermediate in the classical, HMG-CoA reductase pathway (commonly called the mevalonate pathway) and in the non-mevalonate MEP pathway of isoprenoid precursor biosynthesis.

  5. HMG-CoA reductase - Wikipedia

    en.wikipedia.org/wiki/HMG-CoA_reductase

    HMG-CoA reductase (3-hydroxy-3-methyl-glutaryl-coenzyme A reductase, official symbol HMGCR) is the rate-controlling enzyme (NADH-dependent, EC 1.1.1.88; NADPH-dependent, EC 1.1.1.34) of the mevalonate pathway, the metabolic pathway that produces cholesterol and other isoprenoids.

  6. 1-Deoxy-D-xylulose 5-phosphate - Wikipedia

    en.wikipedia.org/wiki/1-Deoxy-D-xylulose_5-phosphate

    The non-mevalonate pathway intermediate 1-deoxy-d-xylulose 5-phosphate (DXP) also acts as a precursor in making isoprenoids in many species such as bacteria, plants, and apicomplexan parasites, contributing to biological diversity. [1]

  7. Non-peptidic antigen - Wikipedia

    en.wikipedia.org/wiki/Non-peptidic_antigen

    Non-peptidic antigens are low-molecular-weight compounds that stimulate human Vγ9/Vδ2 T cells. The most potent activator for Vγ9/Vδ2 T cells is ( E )-4-hydroxy-3-methyl-but-2-enyl pyrophosphate ( HMB-PP ), a natural intermediate of the non-mevalonate pathway of isopentenyl pyrophosphate (IPP) biosynthesis.

  8. Haematopoietic system - Wikipedia

    en.wikipedia.org/wiki/Haematopoietic_system

    Haematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent haematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. [ 10 ] [ 11 ] [ 12 ] It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an ...

  9. Acetoacetyl-CoA - Wikipedia

    en.wikipedia.org/wiki/Acetoacetyl-CoA

    Acetoacetyl CoA is the precursor of HMG-CoA in the mevalonate pathway, which is essential for cholesterol biosynthesis. It also takes a similar role in the ketone bodies synthesis (ketogenesis) pathway of the liver. [1] In the ketone bodies digestion pathway (in the tissue), it is no longer associated with having HMG-CoA as a product or as a ...