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A more recent treatment for severe Raynaud's is the use of botulinum toxin. The 2009 article [37] studied 19 patients ranging in age from 15 to 72 years with severe Raynaud's phenomenon of which 16 patients (84%) reported pain reduction at rest; 13 patients reported immediate pain relief, three more had gradual pain reduction over 1–2 months ...
CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder.The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia.
Raynaud’s phenomenon, which causes parts of the body like the fingers and the toes to go cold and numb, likely stems from two genes, a study published Thursday in the journal Nature ...
Other common symptoms include mechanic's hands, Raynaud's phenomenon, arthritis, and fever. [4] It is still unknown what causes interstitial lung disease associated with antisynthetase syndrome. [5] Many antisynthetase antibodies have been reported with anti-Jo1 being the most prevalent. [6]
The Monroe–Kellie doctrine states that the skull is a fixed and inelastic space and the accumulation of edema will compress vital brain tissue and blood vessels. [8] [38] Surgical treatment of cerebral edema in the context of cerebellar or cerebral infarction is typically done by removing part of the skull to allow expansion of the dura. [38]
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There are also a number of other conditions that affect hands, feet, and parts of the face with associated skin color changes that need to be differentiated from acrocyanosis: Raynaud phenomenon, pernio, acrorygosis, erythromelalgia, and blue finger syndrome. The diagnosis may be challenging in some cases, especially when these syndromes co-exist.
Each agent has its own off-label uses, some examples include Tamsulosin for urinary disorders, Prazosin for post-traumatic stress disorder-related nightmares and Raynaud phenomenon, Phentolamine for hypertensive crisis and extravasation of vasopressors, and Phenoxybenzamine for neurogenic bladder and prostate obstruction. [1]