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  2. Levothyroxine - Wikipedia

    en.wikipedia.org/wiki/Levothyroxine

    For older people (over 50 years old) and people with known or suspected ischemic heart disease, levothyroxine therapy should not be initiated at the full replacement dose. [24] Since thyroid hormone increases the heart's oxygen demand by increasing heart rate and contractility, starting at higher doses may cause an acute coronary syndrome or an ...

  3. Common thyroid drug levothyroxine linked to bone mass loss - AOL

    www.aol.com/lifestyle/common-thyroid-drug...

    Levothyroxine is a frequently prescribed drug in the United States, particularly for older people, as lower thyroid function can be associated with aging.

  4. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...

  5. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [8]

  6. Popular vitamin won’t prevent a fall or fracture in older ...

    www.aol.com/news/popular-vitamin-won-t-prevent...

    “The other thing is that there were some questions about whether high doses might be beneficial of vitamin D and calcium,” Rao said. “But what we found is that there was no dose in our most ...

  7. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    the dose at which toxicity occurs in 50% of cases. LD Lethal Dose the dose at which death occurs in 50% of cases. [6]: 73 [7] [8] TI Therapeutic Index a quantitative measurement of the relative safety of a drug by comparison of the amount of a therapeutic agent that causes toxicity to the amount that causes the therapeutic effect [1]

  8. How to Get Enough Vitamin D in The Winter, According to ... - AOL

    www.aol.com/enough-vitamin-d-winter-according...

    For individuals 1 through 70: 15 mcg of vitamin D per day (600 IU) For individuals 71 and older: 20 mcg of vitamin D per day (800 IU) Manetti notes that IU is "Often the unit used on supplements."

  9. Hashimoto's encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_encephalopathy

    Initial treatment is usually with oral prednisone (50–150 mg/day) or high-dose intravenous methylprednisolone (1 g/day) for 3–7 days. Thyroid hormone treatment is also included if required. Thyroid hormone treatment is also included if required.

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