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Born with advanced rheumatoid arthritis, he endured excruciating pain as a child, and sometimes walked with a cane or used a wheelchair. He also developed hardening of the arteries, and a nearly fatal case of croup. Doctors of his day stated he would never reach the age of thirty.
The use of injected gold compound is indicated for rheumatoid arthritis. [4] Its uses have diminished with the advent of newer compounds such as methotrexate and because of numerous side effects. [4] The efficacy of orally administered gold is more limited than injecting the gold compounds. [5]
Tripterygium wilfordii has been promoted for use in rheumatoid arthritis and psoriasis; however, due to safety concerns this use is not recommended. [1] Evidence is insufficient to deem it effective as a method of birth control for humans. [2]
Sulfasalazine also appears to be most effective in the short-term treatment of rheumatoid arthritis. [120] Hydroxychloroquine, in addition to its low toxicity profile, is considered effective for treatment of moderate RA symptoms. [121] Agents may be used in combination, however, people may experience greater side effects.
Rheumatoid arthritis (RA) is a disorder in which the body's own immune system starts to attack body tissues. [72] The attack is not only directed at the joint but to many other parts of the body. In rheumatoid arthritis, most damage occurs to the joint lining and cartilage which eventually
“The gut microbiome is in constant conversation with the immune system, and so inflammation at a local level can cascade through the immune system and cause system effects,” he added.
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