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2. Peroxisome proliferator-activated receptor - Wikipedia

   en.wikipedia.org/wiki/Peroxisome_proliferator...

   PPAR -alpha and -gamma pathways. In the field of molecular biology , the peroxisome proliferator–activated receptors ( PPARs ) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes . [ 1 ]

3. Peroxisome proliferator-activated receptor alpha - Wikipedia

   en.wikipedia.org/wiki/Peroxisome_proliferator...

   PPAR-α is primarily activated through ligand binding. Endogenous ligands include fatty acids such as arachidonic acid as well as other polyunsaturated fatty acids and various fatty acid-derived compounds such as certain members of the 15-hydroxyeicosatetraenoic acid family of arachidonic acid metabolites, e.g. 15(S)-HETE, 15(R)-HETE, and 15(S)-HpETE and 13-hydroxyoctadecadienoic acid, a ...

4. γ-Linolenic acid - Wikipedia

   en.wikipedia.org/wiki/Γ-Linolenic_acid

   γ-Linolenic acid or GLA (INN: gamolenic acid) is an n−6, or omega-6, fatty acid found primarily in seed oils. When acting on GLA, arachidonate 5-lipoxygenase produces no leukotrienes and the conversion by the enzyme of arachidonic acid to leukotrienes is inhibited.

5. Peroxisome proliferator-activated receptor gamma - Wikipedia

   en.wikipedia.org/wiki/Peroxisome_proliferator...

   Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Alternatively spliced transcript variants that encode different isoforms have been described. [10] The activity of PPARG can be regulated via phosphorylation through the MEK ...

6. Americans get too much omega-6 and not enough omega-3 ... - AOL

   www.aol.com/lifestyle/americans-too-much-omega-6...

   EPA (eicosapentaenoic acid), which reduces inflammation and promotes heart health. ALA (alpha-linolenic acid), which is a plant-based omega-3 that the body converts into DHA and EPA.

7. Essential fatty acid - Wikipedia

   en.wikipedia.org/wiki/Essential_fatty_acid

   Essential fatty acids, or EFAs, are fatty acids that are required by humans and other animals for normal physiological function that cannot be synthesized in the body. [1] [2] ⁠ As they are not synthesized in the body, the essential fatty acids – alpha-linolenic acid (ALA) and linoleic acid – must be obtained from food or from a dietary supplement.