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  2. Afterload - Wikipedia

    en.wikipedia.org/wiki/Afterload

    Afterload is a determinant of stroke volume (in addition to preload, and strength of myocardial contraction). [ 1 ] Following Laplace's law , the tension upon the muscle fibers in the heart wall is the pressure within the ventricle multiplied by the volume within the ventricle divided by the wall thickness (this ratio is the other factor in ...

  3. Preload (cardiology) - Wikipedia

    en.wikipedia.org/wiki/Preload_(cardiology)

    Preload is related to the ventricular end-diastolic volume; a higher end-diastolic volume implies a higher preload. However, the relationship is not simple because of the restriction of the term preload to single myocytes. Preload can still be approximated by the inexpensive echocardiographic measurement end-diastolic volume or EDV.

  4. Pressure–volume loop analysis in cardiology - Wikipedia

    en.wikipedia.org/wiki/Pressure–volume_loop...

    Afterload is the mean tension produced by a chamber of the heart in order to contract. It can also be considered as the ‘load’ that the heart must eject blood against. Afterload is, therefore, a consequence of aortic large vessel compliance, wave reflection, and small vessel resistance (LV afterload) or similar pulmonary artery parameters (RV afterload

  5. Cardiac physiology - Wikipedia

    en.wikipedia.org/wiki/Cardiac_physiology

    A mean SV for a resting 70-kg (150-lb) individual would be approximately 70 mL. There are several important variables, including size of the heart, physical and mental condition of the individual, sex, contractility, duration of contraction, preload or EDV, and afterload or resistance. Normal range for SV would be 55–100 mL.

  6. Frank–Starling law - Wikipedia

    en.wikipedia.org/wiki/Frank–Starling_law

    The three curves illustrate that shifts along the same line indicate a change in preload, while shifts from one line to another indicate a change in afterload or contractility. A blood volume increase would cause a shift along the line to the right, which increases left ventricular end diastolic volume (x axis), and therefore also increases ...

  7. Aortic regurgitation - Wikipedia

    en.wikipedia.org/wiki/Aortic_regurgitation

    Aortic regurgitation causes both volume overload (elevated preload) and pressure overload (elevated afterload) of the heart. [14] The volume overload, due to elevated pulse pressure and the systemic effects of neuroendocrine hormones causes left ventricular hypertrophy (LVH). [9] There is both concentric hypertrophy and eccentric hypertrophy in AI.

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  9. Myocardial contractility - Wikipedia

    en.wikipedia.org/wiki/Myocardial_contractility

    Preload; Afterload; Contractility; By this model, if myocardial performance changes while preload, afterload, heart rate, and conduction velocity are all held constant, then the change in performance must be due to a change in contractility. However, changes in contractility alone generally do not occur. [citation needed] Other examples: