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β-Hydroxy β-methylbutyric acid [note 1] (HMB), otherwise known as its conjugate base, β-hydroxy β-methylbutyrate, is a naturally produced substance in humans that is used as a dietary supplement and as an ingredient in certain medical foods that are intended to promote wound healing and provide nutritional support for people with muscle wasting due to cancer or HIV/AIDS.
β-Hydroxy β-methylbutyryl-coenzyme A (HMB-CoA), also known as 3-hydroxyisovaleryl-CoA, is a metabolite of L-leucine that is produced in the human body. [1] [2] Its immediate precursors are β-hydroxy β-methylbutyric acid (HMB) and β-methylcrotonoyl-CoA (MC-CoA). It can be metabolized into HMB, MC-CoA, and HMG-CoA in humans.
β-Hydroxybutyric acid, also known as 3-hydroxybutyric acid or BHB, is an organic compound and a beta hydroxy acid with the chemical formula CH 3 CH(OH)CH 2 CO 2 H; its conjugate base is β-hydroxybutyrate, also known as 3-hydroxybutyrate. β-Hydroxybutyric acid is a chiral compound with two enantiomers: D-β-hydroxybutyric acid and L-β-hydroxybutyric acid.
Talk:HMB (B-hydroxy B-methylbutyrate monohydrate) Talk:HMB (beta-hydroxy beta-methylbutyrate) Talk:HMB (beta-hydroxy beta-methylbutyric acid) Talk:Hydroxyisovalerate; Talk:Hydroxyisovaleric acid; Talk:Hydroxymethylbutyrate
When combined with an appropriate exercise program, dietary supplementation with β-hydroxy β-methylbutyrate (HMB) has been shown to dose-dependently augment gains in muscle hypertrophy (i.e., the size of a muscle), [29] [30] muscle strength, [29] [31] [32] and lean body mass, [29] [31] [32] reduce exercise-induced skeletal muscle damage ...
β-Hydroxy β-methylbutyric acid (HMB), also known as β-hydroxy β-methylbutyrate (hydroxymethylbutyrate, HMB), is a substance naturally produced in humans that is also used as nutritional supplement. Some of the remaining details in the lead (e.g., mechanism) could also be shortened and simplified. I will work on this once I have a spare moment.
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