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Dilated blood vessels can also develop on the legs, although when they occur on the legs, they often have underlying venous reflux or "hidden varicose veins" (see Venous hypertension section below). When found on the legs, they are found specifically on the upper thigh, below the knee joint and around the ankles.
The small vessels in the skin affected are located in the superficial dermis and include arterioles (small arteries carrying blood to capillaries), capillaries, and venules (small veins receiving blood from capillaries). [5] In general, immune complexes deposit in vessel walls leading to activation of the complement system.
Conditions with leucocytoclasis mainly include hypersensitivity vasculitis (also called leukocytoclastic vasculitis) and cutaneous small-vessel vasculitis (also called cutaneous leukocytoclastic angiitis). An alternative to biopsy can be an angiogram (x-ray test of the blood vessels). It can demonstrate characteristic patterns of inflammation ...
It can cause symptoms such as: Chest pain, pressure, or tightness ... Symptoms can include: Leg or buttock pain with exercise. ... Your doctor will make a small incision into this blood vessel.
It is typically brought on by a precipitating event, such as medication, and is characterized by leukocytoclasia and polymorphonuclear leukocyte infiltration of small blood vessels. [4] The most common signs and symptoms are palpable purpura and joint symptoms. [5] Apart from vasculitis, palpable purpura can also result from cutaneous emboli.
Golfer's vasculitis, also called exercise-induced vasculitis, sport-induced vasculitis, Disney rash, or hiker's rash, is a form of small blood vessel inflammation resulting in a rash. [1] It occurs in the lower legs, and is caused by excessive walking in hot temperatures. It is more common in elderly people.
Cryoglobulinemic vasculitis is a form of inflammation affecting the blood vessels caused by the deposition of abnormal proteins called cryoglobulins.These immunoglobulin proteins are soluble at normal body temperatures, but become insoluble below 37 °C (98.6 °F) and subsequently may aggregate within smaller blood vessels.
Symptoms depend on where the IgA-mediated attack on small blood vessels happens. Some typical places is the skin blood vessels around the buttocks and legs, which leads to significant skin discolouration that looks like blood is pooling under the skin surface - called purpura.
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