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Alternatively spliced transcript variants encoding different isoforms have been identified for HOXC6. Transcript variant two includes the shared exon, and transcript variant one includes only gene-specific exons. [7] HOXC6 plays a role in lymphoma. The HOXC6 isoform, HOXC6-2 is an active carcinogenic for gastric cancer.
HoxC6 was found to play an important role in gastrulation in the vertebrate Xenopus. However, gastrulation was also a target in the Drosophila Antp gene. The anterior–posterior pattern mechanism is highly conserved in these genes, as its function in Xenopus is clear, but it is unclear why it would be a target in Drosophila .
[5] [6] Production of Hox gene products at wrong location in the body is associated with metaplasia and predisposes to oncological disease, e.g. Barrett's esophagus is the result of altered Hox coding and is a precursor to esophageal cancer.
15424 Ensembl ENSG00000172789 ENSMUSG00000022485 UniProt Q00444 P32043 RefSeq (mRNA) NM_018953 NM_175730 RefSeq (protein) NP_061826 NP_783857 Location (UCSC) Chr 12: 54.03 – 54.04 Mb Chr 15: 102.88 – 102.93 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Hox-C5 is a protein that in humans is encoded by the HOXC5 gene. Function This gene belongs to the homeobox ...
Novak Djokovic is speaking out about how he believes he got food poisoning during his 2022 detention in Melbourne, Australia.. In a new February 2025 cover interview with GQ published Thursday ...
The Center for American Progress has estimated that the average American family will face $2,500 in additional costs due to the China tariff alone, and that inflation will increase by at least 1%.
The 12-ounce floret bags were sold at Walmart in 20 states. Affected packages feature a best-by date of December 10, 2024. Fresh broccoli is being recalled due to listeria concerns, according to ...
Learn how to fix common problems singing in to AOL Mail.