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Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...
Amphetamine, which releases NA from vesicles and prevents re-uptake was also used in the treatment of depression at the time with varying success. [196] In 1965 Schildkraut formulated the catecholamine theory of depression. [197] This was subsequently the most widely cited article in the American Journal of Psychiatry. [198]
This is a complete list of clinically approved prescription antidepressants ... approved as a monotherapy for bipolar depression and treatment-resistant depression; ...
During this time development of distinctively different antidepressant agents was also researched. Imipramine became the first clinically useful tricyclic antidepressant (TCA). Imipramine was found to affect numerous neurotransmitter systems and to block the reuptake of norepinephrine and serotonin from the synapse , therefore increasing the ...
Imipramine (Tofranil) is used as a treatment for depression and, occasionally, as a second-line medication to treat depression with melancholic and atypical features. It can also be used to treat ...
The symptoms and the treatment of an overdose are generally the same as for the other tricyclic antidepressants, including anticholinergic effects, serotonin syndrome and adverse cardiac effects. TCAs, particularly nortriptyline, have a relatively narrow therapeutic index , which increase the chance of an overdose (both accidental and intentional).
Antidepressants are recommended as an alternative or additional first step to self-help programs in the treatment of bulimia nervosa. [37] SSRIs (fluoxetine in particular) are preferred over other anti-depressants due to their acceptability, tolerability, and superior reduction of symptoms in short-term trials.
What’s more, once a person has tried two different antidepressants, stayed with each one for long enough to feel the effects, and doesn’t get relief, their depression is considered treatment ...