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Frequency. rare. Richter's transformation (RT), also known as Richter's syndrome, is the conversion of chronic lymphocytic leukemia (CLL) or its variant, small lymphocytic lymphoma (SLL), into a new and more aggressively malignant disease. [1] CLL is the circulation of malignant B lymphocytes with or without the infiltration of these cells into ...
Chronic lymphocytic leukemia. Chronic lymphocytic leukemia ( CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell ). [ 2][ 8] Early on, there are typically no symptoms. [ 2] Later, non-painful lymph node swelling, feeling tired, fever, night sweats, or weight loss for no clear reason may occur ...
Lymphoma in animals. Lymphoma in a Golden Retriever. Lymphoma (lymphosarcoma) in animals is a type of cancer defined by a proliferation of malignant lymphocytes within solid organs such as the lymph nodes, bone marrow, liver and spleen. The disease also may occur in the eye, skin, and gastrointestinal tract .
T-cell acute lymphoblastic leukemia (T-ALL) is a type of acute lymphoblastic leukemia characterized by an aggressive malignant neoplasm of the bone marrow. [6] Acute lymphoblastic leukemia (ALL) is a condition where immature white blood cells accumulate in the bone marrow, subsequently crowding out normal white blood cells [7] and creating a build-up in the liver, spleen, and lymph nodes.
111,000 (2015) [ 10] Acute lymphoblastic leukemia ( ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [ 1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [ 1]
Lymphoma is the most common form of hematological malignancy, or "blood cancer", in the developed world. Taken together, lymphomas represent 5.3% of all cancers (excluding simple basal cell and squamous cell skin cancers) in the United States and 55.6% of all blood cancers.
Signs and symptoms of chronic lymphocytic leukemia commonly precede those of multiple myeloma, sometimes by years. [38] The relationship between the two clones of cells in this combined disease has not been established although one study suggests that the clonal plasma cells and clonal lymphocytes arise from a common hematological stem cell ...
T-cell lymphoma. Micrograph of an enteropathy-associated T-cell lymphoma (upper right of image), a type of T-cell lymphoma. H&E stain. T-cell lymphoma is a rare form of cancerous lymphoma affecting T-cells. [ 1] Lymphoma arises mainly from the uncontrolled proliferation of T-cells and can become cancerous. [ 2]