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The carotid body is a small cluster of peripheral chemoreceptor cells and supporting sustentacular cells situated at the bifurcation of each common carotid artery in its tunica externa. [ 1 ] [ 2 ] The carotid body detects changes in the composition of arterial blood flowing through it, mainly the partial pressure of arterial oxygen , but also ...
Carotid bodies are considered the primary peripheral chemoreceptor and have been shown to contribute more to a hypoxic response. However, in the chronic absence of the carotid body, the aortic body is able to perform a similar respiratory regulatory role, suggesting that it possesses efficacious mechanisms of signal transduction as well. [5]
The carotid body is not labelled but is located within the wall of the internal carotid artery near the bifurcation of the common carotid artery. Glomus type I cells are the chemoreceptor cells found in the carotid body. Glomus cells are the cell type mainly located in the carotid bodies and aortic bodies. Glomus type I cells are peripheral ...
The common carotid arteries are present on the left and right sides of the body. These arteries originate from different arteries but follow symmetrical courses. The right common carotid originates in the neck from the brachiocephalic trunk ; the left from the aortic arch in the thorax.
This signal may be in the form of an action potential, if the chemoreceptor is a neuron, [2] or in the form of a neurotransmitter that can activate a nerve fiber if the chemoreceptor is a specialized cell, such as taste receptors, [3] or an internal peripheral chemoreceptor, such as the carotid bodies. [4]
The carotid sinus baroreceptor can be oversensitive to manual stimulation from the pressure applied at the carotid sinus at the carotid bifurcation. It is a condition known as 'carotid sinus hypersensitivity' (CSH), 'carotid sinus syndrome' or 'carotid sinus syncope', in which manual stimulation causes large changes in heart rate and blood ...
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This is a list of arteries of the human body. The aorta; The arteries of the head and neck. The common carotid artery. The external carotid artery; The triangles of the neck; The internal carotid artery; The arteries of the brain; The arteries of the upper extremity The subclavian artery; The axilla. The axillary artery; The brachial artery ...