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Mirtazapine is sometimes described as a noradrenergic and specific serotonergic antidepressant (NaSSA), [11] although the actual evidence in support of this label has been regarded as poor. [17] It is a tetracyclic piperazine-azepine. [85] Mirtazapine has antihistamine, α 2-blocker, and antiserotonergic activity.
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
It has also been suggested that mirtazapine has no significant serotonergic effects and is therefore not a dual action drug. [34] Bupropion has also been suggested to cause SS, [35] [36] although as there is no evidence that it has any significant serotonergic activity, it is thought unlikely to produce the syndrome. [37]
"Much like muscle and that old saying 'if you don’t use it, you lose it,' using your brain can help protect it, to an extent, from some typical memory decline and slowing," says Carrie Ditzel ...
Here’s a look at the best and worst states in each of our four data categories: mental health provider ratio, percentage of seniors who report 14 or more poor mental health days each month, and ...
People may also be switched to the long-acting antidepressant fluoxetine, which can then be gradually decreased. [12] Approximately 20–50% of people who suddenly stop an antidepressant develop an antidepressant discontinuation syndrome. [187] [13] [188] The condition is generally not serious. [187]
For all adults in the second quarter of 2024, at least 1 in 10 people (13%) reported using mental health counseling in the past year, up from a little over 12% in 2022.
Physical causes are ruled out with a clinical assessment of depression that measures vitamins, minerals, electrolytes, and hormones. [ 2 ] [ 3 ] [ 4 ] Though psychiatric medication is the most frequently prescribed therapy for major depression, [ 5 ] psychotherapy may be effective, either alone or in combination with medication. [ 6 ]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261