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Cobalt poisoning is intoxication caused by excessive levels of cobalt in the body. Cobalt is an essential element for health in animals in minute amounts as a component of vitamin B 12 . A deficiency of cobalt, which is very rare, is also potentially lethal, leading to pernicious anemia .
Vitamin B 12 deficiency is preventable with supplements, which are recommended for pregnant vegetarians and vegans, and not harmful in others. [2] Risk of toxicity due to vitamin B 12 is low. [2] Vitamin B 12 deficiency in the US and the UK is estimated to occur in about 6 percent of those under the age of 60, and 20 percent of those over the ...
In humans most cobalt is found in Vitamin B12.A cobalt atom is visible in the center in this diagram. Cobalt is essential to the metabolism of all animals.It is a key constituent of cobalamin, also known as vitamin B 12, the primary biological reservoir of cobalt as an ultratrace element.
Vitamin B 12 is the most chemically complex of all vitamins, [6] and for humans the only vitamin that must be sourced from animal-derived foods or supplements. [2] [7] Only some archaea and bacteria can synthesize vitamin B 12. [8] Vitamin B 12 deficiency is a widespread condition that is particularly prevalent in populations with low ...
selenium deficiency / selenosis: Cobalt: none NE; NE: Cobalt is available for use by animals only after having been processed into complex molecules (e.g., vitamin B 12) by bacteria. Humans contain only milligrams of cobalt in these cofactors. A deficiency of cobalt leads to pernicious anemia.
Co 2+ - cobalt ions are present in the human body in amounts from 1 to 2 mg. [4] Cobalt is observed in the heart, liver, kidney, and spleen, and considerably smaller quantities in the pancreas, brain, and serum. [4] [5] Cobalt is a necessary component of vitamin B 12 and a fundamental coenzyme of cell mitosis. [5]
The elements listed below as "Essential in humans" are those listed by the US Food and Drug Administration as essential nutrients, [9] as well as six additional elements: oxygen, carbon, hydrogen, and nitrogen (the fundamental building blocks of life on Earth), sulfur (essential to all cells) and cobalt (a necessary component of vitamin B 12).
Some elements otherwise regarded as toxic heavy metals are essential, in small quantities, for human health. These elements include vanadium, manganese, iron, cobalt, copper, zinc, selenium, strontium and molybdenum. [75] A deficiency of these essential metals may increase susceptibility to heavy metal poisoning. [76]