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Reactive lymphocyte surrounded by red blood cells. In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]
Chronic lymphocytic leukemia (CLL) is a type of cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell). [ 2 ] [ 8 ] Early on, there are typically no symptoms. [ 2 ] Later, non-painful lymph node swelling, feeling tired, fever , night sweats , or weight loss for no clear reason may occur.
Atypical cells appear abnormal, but they aren't necessarily cancerous.
Hematological malignancies are malignant neoplasms ("cancer"), and they are generally treated by specialists in hematology and/or oncology. In some centers "hematology/oncology" is a single subspecialty of internal medicine while in others they are considered separate divisions (there are also surgical and radiation oncologists).
CLL/SLL, atypical CLL/SLL, non-CLL/SLL, and MBL-MZ Monoclonal B-cell lymphocytosis (MBL) is an asymptomatic condition in which individuals have increased blood levels of particular subtypes of monoclonal lymphocytes (i.e. an aberrant and potentially malignant group of lymphocytes produced by a single ancestral cell).
Hodgkin lymphoma (HL) is a type of lymphoma in which cancer originates from a specific type of white blood cell called lymphocytes, where multinucleated Reed–Sternberg cells (RS cells) are present in the patient's lymph nodes. [2] [8] The condition was named after the English physician Thomas Hodgkin, who first described it in 1832.
Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). [7] The name typically refers to just the cancerous versions rather than all such tumours. [7]
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