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Implants, made of synthetic materials, are naturally coated by a biofilm by the body, which may function as a favorable medium for bacteria growth. Implant failure due to bacterial infection of the implant can occur at any point of implant lifetime. Bacteria may already reside on the implant or be introduced during the implantation.
Acute infections (in which the biofilm is thought to be immature) are usually treated using the DAIR technique; debridement, systemic and local antibiotics, and implant retention (the implant is not removed). [4] [2] However, the mobile, easily interchangeable components of the implant are often replaced in the DAIR approach. [4]
Although S. epidermidis is not usually pathogenic, patients with compromised immune systems are at risk of developing infection. These infections are generally hospital-acquired. [4] S. epidermidis is a particular concern for people with catheters or other surgical implants because it is known to form biofilms that grow on these devices. [5]
Breast implants are one of the most popular cosmetic procedures — making it into the top-five list of cosmetic surgeries in 2020, even with a pandemic-related decline — promising fuller and ...
It was found that in the absence of clinical presentation of infection, impregnated bacteria could form a biofilm around an implant, and this biofilm can remain undetected via contemporary diagnostic methods, including swabbing. Implant biofilm is frequently present in "aseptic" pseudarthrosis cases.
Staphylococcus aureus is a significant cause of chronic biofilm infections on medical implants, and the repressor of toxins is part of the infection pathway. [30] Staphylococcus aureus can lie dormant in the body for years undetected. Once symptoms begin to show, the host is contagious for another two weeks, and the overall illness lasts a few ...
Persister cells are highly enriched in biofilms, and this makes biofilm-related diseases difficult to treat. Examples are chronic infections of implanted medical devices such as catheters and artificial joints, urinary tract infections , middle ear infections and fatal lung disease.
Free-flap breast reconstruction is a type of autologous-tissue breast reconstruction applied after mastectomy for breast cancer, without the emplacement of a breast implant prosthesis. As a type of plastic surgery, the free-flap procedure for breast reconstruction employs tissues, harvested from another part of the woman's body, to create a ...