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o-Toluidine (ortho-toluidine) is an organic compound with the chemical formula CH 3 C 6 H 4 NH 2. It is the most important of the three isomeric toluidines. It is a colorless liquid although commercial samples are often yellowish. It is a precursor to the herbicides metolachlor and acetochlor. [2]
American chemist Linus Pauling coined the term "orthomolecular" in the 1960s to mean "the right molecules in the right amounts" (ortho-in Greek implies "correct"). [11] Proponents of orthomolecular medicine hold that treatment must be based on each patient's individual biochemistry. [12] [13]
ortho- and meta-toluidines are viscous liquids, but para-toluidine is a flaky solid. This difference is related to the fact that the p-toluidine molecules are more symmetrical. p-Toluidine can be obtained from reduction of p-nitrotoluene. p-Toluidine reacts with formaldehyde to form Tröger's base.
Ortho-McNeil was found liable in two 2013 civil suits by women who gave birth to children with birth defects after taking Topamax while pregnant. The jury found that they negligently failed to warn the patients and their doctors of the risks associated with Topamax when used by patients during pregnancy. [ 5 ]
In 1963, Ortho introduced the second oral contraceptive available in the United States (Ortho-Novum 10 and Ortho-Novum 2, produced by Syntex). In 1964, Ortho bought rights to and marketed the Gynekoil (Margulies Coil) and Lippes Loop inert plastic IUDs in the United States until the mid-1970s and 1985, respectively.
Plus, your body is simply not used to that level of consumption. “You can't just assume that, ‘Oh, it's been two weeks since I've had it. So I'm just gonna eat this entire plate of food,' " he ...
2-Tolidine (orthotolidine, o-tolidine; not to be confused with o-toluidine) is an organic compound with the chemical formula (C 6 H 4 (CH 3)NH 2) 2.Several isomers are known; the 3-tolidine derivative is also important commercially.
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