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Autoimmune urticaria is characterized by the presence of autoantibodies, which are antibodies that the immune system mistakenly produces against the body's own cells.In the case of autoimmune urticaria, these autoantibodies primarily target the high-affinity IgE receptor (FcεRI) on mast cells and basophils, or less commonly, IgE itself.
Urticarial vasculitis (also known as "chronic urticaria as a manifestation of venulitis", "hypocomplementemic urticarial vasculitis syndrome", "hypocomplementemic vasculitis" and "unusual lupus-like syndrome") [1] is a skin condition characterized by fixed urticarial lesions that appear histologically as a vasculitis.
Possibly an immune system disorder but not autoimmune. Gastrointestinal pemphigoid: No consistent evidence of association with autoimmunity. Hypogammaglobulinemia: An immune system disorder but not autoimmune. Idiopathic giant-cell myocarditis: No consistent evidence of autoimmune cause though the disease has been found comorbid with other ...
PLAID syndrome is an inherited condition characterised by antibody deficiency and immune dysregulation, first described in 2012. The name is an acronym of "PLCG2-associated antibody deficiency and immune dysregulation". It is characterised by cold-induced urticaria, autoimmunity, atopy and humoral immune deficiency. [1]
Erythema toxicum neonatorum is related to activation of the immune system, but its exact cause is unknown. Many inflammatory factors have been detected in erythema toxicum neonatorum lesions, including IL-1alpha, IL-1beta, IL-8, and eotaxin. [5] [4] These molecules cause redness and swelling in the skin and attract immune cells. [10]
The cause of physical urticaria is unknown but it has been suggested to be an autoimmune disease, suggesting that antibodies, which are produced by the immune system to protect humans from foreign microbes, are binding to body tissue and damaging it. [8] In some cases physical urticaria can be a symptom of an underlying health issue such as: [9 ...
More than 100,000 people in the U.S. have become allergic to red meat since 2010 because of a weird syndrome triggered by tick bites, according to a government report released Thursday. A second ...
Symptoms are thought to be the result of histamine being released by mast cells on the surface of the skin. Despite the lack of antigens , histamine causes the skin to swell in affected areas. If the membrane that surrounds the mast cells is too weak, it will easily and rapidly break down under physical pressure, which then causes an allergic ...