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  2. Granulomatosis with polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Granulomatosis_with...

    On histopathological examination, a biopsy will show leukocytoclastic vasculitis with necrotic changes and granulomatous inflammation (clumps of typically arranged white blood cells) on microscopy. These granulomas are the main reason for the name granulomatosis with polyangiitis, although it is not an essential feature.

  3. Systemic vasculitis - Wikipedia

    en.wikipedia.org/wiki/Systemic_vasculitis

    Necrotizing vasculitis, also called systemic necrotizing vasculitis, [1] is a general term for the inflammation of veins and arteries that develops into necrosis and narrows the vessels. [ 2 ] Tumors , medications, allergic reactions , and infectious organisms are some of the recognized triggers for these conditions, even though the precise ...

  4. Microscopic polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Microscopic_polyangiitis

    The neutrophils bind to p-ANCAs and subsequently release inflammatory cytokines, reactive oxygen species and lytic enzymes that cause endothelial injury resulting to inflammation and necrosis of the small vessels. [4] The damage that is caused in the kidneys is specifically called necrotizing and crescentic glomerulonephritis. [5]

  5. Eosinophilic granulomatosis with polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Eosinophilic_granulomatos...

    Eosinophilic granulomatosis with polyangiitis consists of three stages, but not all patients develop all three stages or progress from one stage to the next in the same order; [7] whereas some patients may develop severe or life-threatening complications such as gastrointestinal involvement and heart disease, some patients are only mildly affected, e.g. with skin lesions and nasal polyps. [8]

  6. Scleritis - Wikipedia

    en.wikipedia.org/wiki/Scleritis

    Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera.The disease is often contracted through association with other diseases of the body, such as granulomatosis with polyangiitis or rheumatoid arthritis.

  7. Bird fancier's lung - Wikipedia

    en.wikipedia.org/wiki/Bird_fancier's_lung

    Standard bronchoscopy usually shows chronic inflammation of lung tissue, and granulomas with poorly-defined margins. [1] Lung biopsy usually reveals non-necrotizing granulomatous inflammation. [7] It also shows "foamy" macrophages and crystals of oxalic acid. [3] Hyperplasia tends to occur in type 1 pneumocytes and not in type 2 pneumocytes. [3]

  8. Granulomatous mastitis - Wikipedia

    en.wikipedia.org/wiki/Granulomatous_mastitis

    Special forms of granulomatous mastitis occur as complication of diabetes. Some cases are due to silicone injection (Silicone-induced granulomatous inflammation) or other foreign body reactions. [2] [3] Idiopathic granulomatous mastitis (IGM) is defined as granulomatous mastitis without any other attributable cause such as those above mentioned.

  9. Granuloma - Wikipedia

    en.wikipedia.org/wiki/Granuloma

    Crohn's disease is an inflammatory condition of uncertain cause characterized by severe inflammation in the wall of the intestines and other parts of the abdomen. Within the inflammation in the gut wall, granulomas are often found and are a clue to the diagnosis. [13]