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Date: 1 February 2024: Source: Own work. Reference for findings: Carlos C. Diez Freire, M.D., Shahla Masood, M.D.. Apocrine metaplasia.Pathology Outlines.
Apocrine ductal carcinoma in situ (ACDIS) is a very rare breast carcinoma which is regarded as a variant of the ductal carcinoma in situ breast tumors. ACDIS tumors have microscopic histopathology features that are similar to pure apocrine carcinoma of the breast tumors but differ from them in that they are completely localized, i.e. have not invaded nearby tissues or metastasized to distant ...
Syringocystadenoma papilliferum is a rare non-malignant adnexal neoplasm that develops from apocrine or eccrine sweat glands and can be identified histologically by cystic, papillary, and ductal invaginations into the dermis lined by double-layered outer cuboidal and luminal high columnar epithelium and connected to the epidermis.
Papillomatosis of the breast (PB) is a rare, benign, epitheliosis-like lesion, i.e. an overgrowth of the cells lining the ducts of glands that resembles a papilla (i.e. small rounded protuberance) or nipple-like nodule/tumor. PB tumors develop in the apocrine glands of the breast.
Fibrocystic breast changes is a condition of the breasts where there may be pain, breast cysts, and breast masses. [1] The breasts may be described as "lumpy" or "doughy". [3] Symptoms may worsen during certain parts of the menstrual cycle due to hormonal stimulation. [1] These are normal breast changes, not associated with cancer. [2]
Fig. 2 Breast apocrine carcinoma Fig. 3 Breast apocrine carcinoma. The microscopic histopathology of PACB tumors prepared with hematoxylin and eosin staining shows that >90% of the tumors consist of apocrine gland-like tissue. The lesions must also show that tumor cells have broken through their ducts of origin to invade adjacent tissue in at ...
The disease affects regions that are rich in apocrine secretions. [4] 65% EMPD occurs at the vulva, [15] followed by 15% at perianal areas and 14% at the male genitalia. [2] In terms of the vulva, the labia majora is the site that is most often involved, followed by labia minora, clitoris and perineum. [16]
Micrograph showing apocrine-type metaplasia of the breast with typical oncocytes. [2] H&E stain. Oncocytes (left of image), as seen in a renal oncocytoma. H&E stain. An oncocyte is an epithelial cell characterized by an excessive number of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. Oncocytes can be benign or malignant.